Esther P. Black, Ph.D., University of Kentucky, College of Pharmacy
Dual targeted therapy: can MEK inhibition improve response and reduce acquired resistance in EGFR-dependent NSCLC?

This grant is being fully funded by the Kim Massengill Seibert Fund for Lung Cancer Research, through the Joan’s Legacy: Uniting Against Lung Cancer Grant Program.

Rolf A. Brekken, Ph.D., University of Texas Southwestern Medical Center: Identification of Tumor Cell-derived Factors Associated with Resistance to Anti-VEGF Therapy in Lung Cancer

Recipient of the Randall Bridwell Lung Cancer Research Grant.

Wenrui Duan, Ph.D., Ohio State University : Treatment of Spontaneous Non Small cell Lung Cancer in Transgenic Mice with PRIMA-1, a Novel Anti Cancer Agent

Recipient of the LUNGevity Foundation/Joan’s Legacy Research Grant. Funded equally by Joan's Legacy and the LUNGevity Foundation.

Sizhi Paul Gao, M.D., Ph.D., Memorial Sloan-Kettering Cancer Center: IL-6/Jak Inhibition for the Treatment of Lung Cancer

This grant is being fully funded by Elliot’s Legacy, through the Uniting Against Lung Cancer Grant Program.

Randolph Hastings, M.D., Ph.D., Veterans Medical Research Foundation: Determinants of Lepidic Growth in Bronchioalveolar Carcinoma

Recipient of the Joan Scarangello Research Grant

Faye Johnson, M.D., Ph.D., University of Texas - MD Anderson Cancer Center : The Receptor Tyrosine Kinase EphA2: A Novel Therapeutic Target for Non-Small Cell Lung cancer

This grant is being fully funded by the Caine Halter Fund for Lung Cancer Research, through the Uniting Against Lung Cancer Grant Program.

William Y. Kim, M.D., University of North Carolina at Chapel Hill : The Role of HIF2 in LKB1-defective Lung Tumors

This grant is being fully funded by the Thomas G. Labrecque Foundation, through the Joan’s Legacy: Uniting Against Lung Cancer Grant Program.

Rachel M.A. Linger, Ph.D., University of Colorado, Denver: Synergistic Interaction Between Standard Chemotherapy and Novel Biologically Targeted Therapy for Treatment of Non-Small Cell Lung Cancer

This grant is being fully funded by Elliot’s Legacy, through the Uniting Against Lung Cancer Grant Program.

Philip C. Mack, Ph.D., University of California, Davis: Detection of KRAS and EGFR Mutations in Shed DNA in Plasma from NSCLC Patients Treated with Cetuximab or Gefitinib

This grant is being fully funded by Elliot’s Legacy, through the Uniting Against Lung Cancer Grant Program.

Poulikos I. Poulikakos, Ph.D., Memorial Sloan-Kettering Cancer Center: Targeting Oncogenic Raf in Non-Small Cell Lung Cancer: Identification and Characterization of Specific Molecular Subtypes of NSCLC

This grant is being fully funded by the Thomas G. Labrecque Foundation, through the Joan’s Legacy: Uniting Against Lung Cancer Grant Program.

Rajagopal Ramesh, Ph.D., University of Texas - MD Anderson Cancer Center: Targeted IMAT Multifunctional Nanoparticles for Bronchioalveolar Lung Cancer

Recipient of the Felice Lipit Jentis Memorial/Joan’s Legacy Research Grant. Funded equally by Joan's Legacy and The Felice Lipit Jentis Memorial BAC Research Trust.

Lynne Regan, Ph.D., Yale University: Development of a Novel Class of Therapeutics for Bronchioalveolar Carcinoma

Recipient of the LUNGevity Foundation/Joan’s Legacy Research Grant. Funded equally by Joan's Legacy and the LUNGevity Foundation.

E. Aubrey Thompson, Ph.D., Mayo Clinic: The Role of Phospholipase D1 in EGFR Addiction

Recipient of the Laura Geller Research Grant.

Yuzhi Yin, M.D., Ph.D., Georgetown University: Musashi1 as a Stem Cell Marker and Therapeutic Target for Bronchioalveolar Lung Cancer

Recipient of the Mary Jo’s Fund to Fight Cancer/Joan’s Legacy Research Grant. Funded equally by Joan's Legacy and Mary Jo’s Fund to Fight Cancer.

Mark M. Fuster, M.D., University of California, San Diego: Novel Targeting for Two Faces of Bronchioalveolar Carcinoma   

Yixuan Gong, Ph.D., Memorial Sloan-Kettering Cancer Center: Exploiting Apoptotic Pathways to Enhance Responses of Mutant EGFR-dependent Lung Adenocarcinoma to Kinase Inhibitors

Recipient of the Barbara Parisi Lung Cancer Research Grant.

David Neil Hayes, M.D., MPH, University of North Carolina, Chapel Hill: Molecular Subtypes of Non-Small Cell Lung Cancer

This grant is being fully funded by the Thomas G. Labrecque Foundation, through the Joan’s Legacy Grant Program.

John Heymach, M.D., Ph.D., MD Anderson Cancer Center: EGFR/estrogen Interactions: Role in Bronchioalveolar Carcinoma and Gender Differences in the Efficacy of Antiangiogenic Therapy

Recipient of the LUNGevity Foundation/Joan’s Legacy Research Grant. Funded equally by Joan's Legacy and the LUNGevity Foundation.

Federico Innocenti, Ph.D., University of Chicago: Genetics of VEGFR-2 in Bronchioalveolar Carcinoma 

With funding from the Sandra Phillips Britt Fund for Lung Cancer Research

Carla F. Kim, Ph.D., Children's Hospital Boston: Isolation and Characterization of Bronchioalveolar Carcinoma Stem Cells 

Recipient of the LUNGevity Foundation/Joan’s Legacy Research Grant. Funded equally by Joan's Legacy and the LUNGevity Foundation.

David J. Kwiatkowski, MD, Ph.D., Dana-Farber Cancer Institute: Role of TSC Genes in Lung Cancer

This grant is being fully funded by the Thomas G. Labrecque Foundation, through the Joan’s Legacy Grant Program.

Hayley McDaid, Ph.D., Albert Einstein College of Medicine: Mechanisms of RAS and RAF-mediated Regulation of Cap-dependent Translation in NSCLC  

Recipient of the LUNGevity Foundation/Joan’s Legacy Research Grant. Funded equally by Joan's Legacy and the LUNGevity Foundation.

Raffaella Sordella, PH.D., Cold Spring Harbor Laboratory: Role of Estrogen in Regulating the Activity of EGFR in NSCLC 

E. Alejandro Sweet-Cordero, M.D., Stanford University: Functional Analysis of Novel Oncogenic Kras Effector Pathways  

With funding from the Rogerio Lilenbaum Fund   

Matthew K. Topham, M.D., University of Utah: Role of COX-2 and Inflammation in Tumors with Activating EGFR Mutations

Recipient of the Kate McMullen Foundation /Joan’s Legacy Research Grant. Funded equally by Joan's Legacy and the Kate McMullen Foundation.

Bingcheng Wang, Ph.D., MetroHealth Medical Center, Case Western Reserve Medical Center: Harnessing the Intrinsic Tumor Suppressor Activities of EphA2 Kinase for Lung Cancer Therapy

Ruth A. Gjerset, Ph.D., Sidney Kimmel Cancer Center: Novel Gene Delivery Strategy for Lung Cancer Treatment

He Biao, Ph.D., University of California, San Francisco: Identification of Novel Wnt Signaling-Related Therapeutic Targets Against Bronchioalveolar Carcinoma

Christopher R. Herzog, Ph.D., Pennsylvania State University College of Medicine: Study of FOX03a in Lung Cancer Therapy

Carolyn Klinge, Ph.D., University of Louisville School of Medicine: Estrogen Receptor Beta Interacting Proteins in Lung Adenocarcinoma

Recipient of the LUNGevity Foundation/Joan’s Legacy Research Grant. Funded equally by Joan's Legacy and the LUNGevity Foundation.

Ite A. Laird-Offringa, Ph.D., USC/Norris Cancer Center: Epigenetic Alterations During Progression from Atypical Adenomatous Hyperplasia to Bronchioalveolar Carcinoma and Lung Adenocarcinoma

This grant is being fully funded by the Thomas G. Labrecque Foundation, through the Joan’s Legacy Grant Program.

Edwina C. Lerner, Ph.D., University of Pittsburgh: Targeting the X-Linked Gene Gastrin Releasing Peptide Receptor in Combination with Epidermal Growth Factor Receptor Inhibitors in Non-Small Cell Lung Cancer

Viji Shridhar, Ph.D., Mayo Clinic College of Medicine: Functional Characterization of HSulf-1 Loss in Bronchioalveolar Carcinoma

Recipient of the Felice Lipit Jentis Memorial/Joan’s Legacy Research Grant. Funded equally by Joan's Legacy and The Felice Lipit Jentis Memorial BAC Research Trust.

Masaaki Tamura, D.V.M., Ph.D., Kansas State University College of Veterinary Medicine: IFN-Beta Expressing Stem Cell Therapy for Bronchioalveolar Carcinoma

Rajiv Dhand, Ph.D., University of Missouri School of Medicine: Tolerance and Safety of Direct Targeted Aerosol Chemotherapy

Dennis A. Wigle, B.Sc., M.Sc., M.D., Ph.D., Mayo Clinic: A Single Nucleotide Polymorphism (SNP) Association Study to Investigate the Genetic Basis of Bronchioalveolar Carcinoma

This grant is being fully funded by the Thomas G. Labrecque Foundation, through the Joan’s Legacy Grant Program.

William W. Young, Jr., Ph.D., University of Louisville Research Foundation: MUC1 Splice Variants and Estrogen Receptors in Lung Adenocarcinoma

This grant is being fully funded by the Thomas G. Labrecque Foundation, through the Joan’s Legacy Grant Program.

Sanford H. Barsky, M.D., Ohio State University College of Medicine: The Bone Marrow Stem Cell Origin of Lung BAC / PAC

David Mu, Ph.D., Cold Spring Harbor Laboratory: Discovery and Characterization of Novel Amplified Lung Cancer Genes in Women

William Pao, M.D., Ph.D., Memorial Sloan-Kettering Cancer Center: Acquired Resistance to Targeted Therapy

Recipient of the Barbara Parisi Lung Cancer Research Grant.

David N. Reisman, M.D., Ph.D., University of Michigan: Alteration in the SWI/SNF Chromatin Remodeling Complex in Bronchioalveolar Carcinoma

Eric Haura, M.D., H. Lee Moffitt Cancer Center & Research Institute: Targeting SRC and Stat3 Signaling in EGFR-Driven Non-Small Cell Lung Cancer

Recipient of the Joan's Legacy/LUNGevity Foundation Lung Cancer Research Grant. Funded equally by Joan's Legacy and the LUNGevity Foundation.

Charles A. Powell, M.D., Columbia  University: Acquisition of Invasiveness in Lung Adenocarcinoma

Recipient of the Joan's Legacy/Thomas G. Labrecque Foundation Lung Cancer Research Grant. Funded equally by Joan's Legacy and the Thomas G. Labrecque Foundation.

Julian R. Molina, M.D., Ph.D., Mayo Clinic Cancer Center: Molecular Determinants of Intrapulmonary Dissemination and Metastasis of Bronchioalveolar Carcinoma (BAC) of the Lung

Chong-xian Pan, M.D., Ph.D., University of California, Davis: Tissue-specific Gene Therapy for Bronchioalveolar Carcinoma

Dr. Kwok-Kin Wong, M.D., Ph.D., Dana-Farber Cancer Institute at Harvard University: Novel Human Lung Cancer Gene Discovery